The Blackwall Tunnel has been closed northbound and is not expected to reopen until Wednesday after a vehicle fire yesterday.
The incident happened on Sunday at around 17.45 and two people were taken to hospital - one due to smoke inhalation and one with an ankle injury.
Transport for London say that the road surface, lighting and CCTV systems were damaged in the fire and TFL engineers are working 24 hours a day to repair the damage.
The closure of the northbound tunnel has caused gridlock on surrounding roads, with motorists advised to use the Dartford river crossing, Rotherhithe Tunnel, Woolwich Ferry or Tower Bridge to cross the Thames.
Greenwich Council responded to the closure by saying that it underlined the need for additional river crossings.
Cllr Peter Brooks, Deputy Leader of the Council, said, “The travel difficulties experienced this morning – and which are forecast to last at two more days – starkly underline the dangers for Londoners of relying so heavily on the Blackwall Tunnel.
“Greenwich Council has consistently pressed for a package of further river crossings, to relieve the pressure on the crossing at Blackwall, which is why we were extremely disappointed at the decision of the Mayor of London to scrap plans for the Thames Gateway crossing.
“We are continuing to press the Mayor to put the Thames Gateway crossing – together with a new crossing at Silvertown – firmly back on the agenda.”
UPDATE: The Blackwall tunnel reopened tonight after TfL engineers worked quickly to repair fire damage, well ahead of the initial estimate that it wouldn't reopen until Wednesday.
Garrett Emmerson, Chief Operating Officer, London Streets, said: 'I would like to pay tribute to the tireless work of the emergency services, tunnel engineers and many others who have ensured we have been able to reopen the tunnel so quickly.